The Apis Flora Propolis Extract, the first propolis extract sold in Brazil, was introduced in 1983. The National Health Surveillance Agency - ANVISA conducts routine inspections and monitoring of Apis Flora, and in 2011 it issued their Beehive a certificate for conformity with excellent medicine manufacturing methods.
In the interior of So Paulo, in Ribeiro Preto, Apis Flora has three facilities that handle manufacturing, storage, logistics, and administrative tasks. They have four production divisions: pharmaceutical ingredients, herbal and biotechnological medicines, natural foods and nutraceuticals, and cosmetics and personal care items.