과립형 만니톨 마켓 오버뷰 2026

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만니톨
최종 업데이트
2026-05-01
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과립형 만니톨에 대한 글로벌 공급업체 거래, 수출 활동 및 가격 벤치마크

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과립형 만니톨 국가별 공급업체 거래 및 단가 요약

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국가전년 대비 변화거래 건수2025-062025-072025-082025-092025-102025-112025-122026-012026-022026-032026-042026-05
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과립형 만니톨 Global Supply Chain Coverage
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과립형 만니톨 상위 바이어, 수입업체 및 수요 파트너

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(인도)
최근 수입 거래: 2026-03-30
임직원 규모: 직원 51 - 100명
매출액: 매출 USD 10M - 50M
산업군: 식음료 서비스업음료 제조식품 제조
밸류체인 역할: 방글라데시
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Classification

Product TypeIngredient
Product FormGranular crystalline powder
Industry PositionFood additive and pharmaceutical excipient (polyol)

Market

Granular mannitol is a globally traded polyol used as a food additive (INS 421 / E 421) and as a pharmaceutical excipient, with demand tied to sugar-free confectionery and solid oral dosage manufacturing. UN Comtrade (via World Bank WITS) trade statistics for HS 290543 indicate exports led by France and China, with additional significant export capacity in the United States and multiple EU member states. Major import demand centers include India, the United States, Japan, Germany, and the Netherlands, reflecting both food manufacturing and pharmaceutical supply chains. Market dynamics are shaped by specification-driven purchasing (food additive vs. multi-compendial/pharma grades), logistics reliability for bulk powders, and quality-system compliance for high-purity applications.
Major Producing Countries
  • 프랑스Large industrial production footprint inferred from being the top exporter by value in UN Comtrade/WITS 2024 (HS 290543).
  • 중국Major global exporter by quantity in UN Comtrade/WITS 2024 (HS 290543), indicating substantial manufacturing capacity.
  • 미국Notable exporter in UN Comtrade/WITS 2024 (HS 290543); also a major import market, reflecting domestic consumption and downstream manufacturing.
  • 이탈리아Significant exporter in UN Comtrade/WITS 2024 (HS 290543), consistent with EU polyol/excipient manufacturing presence.
  • 네덜란드Material exporter and major import gateway in UN Comtrade/WITS 2024 (HS 290543), consistent with regional distribution roles.
Major Exporting Countries
  • 프랑스Top exporter by value in UN Comtrade/WITS 2024 for HS 290543 (Mannitol).
  • 중국Top-tier exporter in UN Comtrade/WITS 2024 for HS 290543, leading by quantity among the listed top exporters.
  • 미국Top-tier exporter in UN Comtrade/WITS 2024 for HS 290543.
  • 이탈리아Top-tier exporter in UN Comtrade/WITS 2024 for HS 290543.
  • 네덜란드Notable exporter in UN Comtrade/WITS 2024 for HS 290543.
  • 체코Notable exporter in UN Comtrade/WITS 2024 for HS 290543.
  • 인도Exporter in UN Comtrade/WITS 2024 for HS 290543, though also the top importer by value.
Major Importing Countries
  • 인도Top importer by value in UN Comtrade/WITS 2024 for HS 290543 (Mannitol).
  • 미국Top importer by value in UN Comtrade/WITS 2024 for HS 290543.
  • 일본Top importer by value in UN Comtrade/WITS 2024 for HS 290543.
  • 독일Top importer by value in UN Comtrade/WITS 2024 for HS 290543.
  • 네덜란드Top importer by value in UN Comtrade/WITS 2024 for HS 290543; also a notable exporter, consistent with distribution/re-export activity.
  • 멕시코Significant importer by value in UN Comtrade/WITS 2024 for HS 290543.
  • 영국Significant importer by value in UN Comtrade/WITS 2023 for HS 290543 (latest readily available in sourced extracts).
Supply Calendar
  • France:Jan, Feb, Mar, Apr, May, Jun, Jul, Aug, Sep, Oct, Nov, DecIndustrial chemical production; supply is generally year-round with potential sensitivity to plant maintenance and energy costs.
  • China:Jan, Feb, Mar, Apr, May, Jun, Jul, Aug, Sep, Oct, Nov, DecIndustrial chemical production; supply is generally year-round with potential sensitivity to policy, logistics, and utility disruptions.
  • United States:Jan, Feb, Mar, Apr, May, Jun, Jul, Aug, Sep, Oct, Nov, DecIndustrial chemical production; supply is generally year-round.

Specification

Physical Attributes
  • White, odourless/crystalline powder (JECFA specification description).
  • Granular and directly compressible grades are marketed for applications such as tablets, granules, and pellets (example: granular/direct compression product grades).
Compositional Metrics
  • JECFA specification: assay not less than 96.0% and not more than 102.0% on the dried basis.
  • JECFA specification includes purity-related limits and identity tests relevant for international food additive trade (e.g., loss on drying, specific rotation, pH, ash, chlorides/sulfates, nickel, reducing sugars, lead).
  • Pharmacopeial-grade mannitol is standardized via harmonized excipient monographs (e.g., USP harmonization posting for Mannitol excipient).
Grades
  • Codex/GSFA food additive: Mannitol (INS 421) with provisions by food category (often GMP or specified limits).
  • EU food additive: E 421 (Mannitol) listed under Regulation (EC) No 1333/2008.
  • Pharmaceutical excipient grades marketed for direct compression and other solid dosage processing (granulated or spray-dried grades).
ProcessingCommercial production is commonly based on catalytic hydrogenation of glucose/fructose-containing sugar solutions; fermentation routes are also recognized in regulation and technical literature.Functional performance is particle-engineered in some grades (e.g., granulated or spray-dried) to improve flow/compressibility for direct compression tableting.

Supply Chain

Value Chain
  • Sugar feedstock (glucose/fructose/sucrose or related sugar alcohols) → reduction/hydrogenation or fermentation → purification → crystallization → drying → milling/sieving (granular control) → bulk packaging → distribution to food manufacturers and pharma/nutraceutical excipient users.
Demand Drivers
  • Sugar-free and reduced-sugar confectionery and chewing gum formulations where mannitol is used as a sweetener/bulking agent and processing aid under food additive frameworks.
  • Pharmaceutical and nutraceutical solid oral dose manufacturing demand for direct-compression and granular excipient grades.
Temperature
  • Typically handled as a dry bulk powder; moisture control and dry storage are important to maintain flowability and prevent caking in distribution.

Risks

Quality And Compliance HighSpecification-driven demand (food additive vs. multi-compendial/pharmacopeial grades) makes mannitol supply vulnerable to batch rejections and sudden shortfalls when impurities or contaminants exceed limits (e.g., metals such as nickel and other purity parameters covered by JECFA specifications) or when excipient quality-system expectations tighten for sensitive drug applications.Use qualified multi-source supplier strategies; require JECFA/GSFA alignment for food use and pharmacopeial-grade documentation where applicable; implement incoming QC testing focused on key impurity/metal markers and lot traceability.
Regulatory Compliance MediumPermitted uses and labeling expectations vary by jurisdiction; for example, U.S. regulation specifies both permitted food uses and a laxative-effect warning statement tied to daily ingestion thresholds, creating compliance risk for cross-border finished goods containing mannitol.Maintain jurisdiction-specific regulatory mapping (Codex, EU additive rules, and key national frameworks) and validate finished-product labeling thresholds and use levels per destination market.
Trade Concentration MediumTrade data for HS 290543 indicate export supply is concentrated among a limited set of exporting countries (notably France, China, and the United States), while major import demand clusters in India, the United States, Japan, and key EU hubs; disruptions affecting one of these export centers can quickly tighten availability for import-reliant markets.Monitor UN Comtrade/WITS trade flows for emerging shifts; hold safety stocks for high-service channels; qualify alternative origins and routes, especially for high-spec grades.
Process Safety LowHydrogenation-based manufacturing involves high-pressure hydrogen handling and catalysts, creating operational risk that can translate into supply interruptions in the event of plant incidents or extended maintenance.Assess supplier operational resilience (process safety programs, maintenance planning) and diversify across independent manufacturing sites where possible.
Sustainability
  • Energy intensity and purification complexity in common catalytic hydrogenation-based production pathways can raise cost volatility and emissions-management scrutiny for producers and buyers (especially for high-purity grades).
  • Dependence on carbohydrate feedstocks (sugar streams) links mannitol cost and availability indirectly to agricultural and industrial sugar markets.

FAQ

What is granular mannitol classified as in global food additive systems?In Codex GSFA, mannitol is listed as INS 421, with functional classes such as sweetener, bulking agent, humectant, stabilizer, thickener, and anticaking agent. In the EU additive system it is listed as E 421 (mannitol).
Which countries are the largest exporters and importers of mannitol in recent UN Comtrade statistics?For HS 290543 (mannitol), World Bank WITS (sourced from UN Comtrade) lists France and China among the top exporters in 2024, along with the United States and Italy. The top importers in 2024 include India, the United States, Japan, Germany, and the Netherlands.
How is mannitol commonly manufactured for commercial supply?U.S. regulation recognizes production via electrolytic reduction or catalytic hydrogenation of glucose/fructose sugar solutions, and via fermentation routes (including use of the yeast Zygosaccharomyces rouxii or specified bacterial cultures).
What are the key quality parameters that typically matter in mannitol trade and procurement?International specifications such as JECFA include identity and purity controls (including assay on a dried basis, loss on drying, and impurity limits that can include metals like nickel and reducing sugars). Buyers selecting higher-spec material may also require alignment with pharmacopeial excipient monographs.

Sources

World Bank WITS (UN Comtrade) — Mannitol exports by country (HS 290543), 2024
World Bank WITS (UN Comtrade) — Mannitol imports by country (HS 290543), 2024
FAO — GSFA Online: Food Additive Details for Mannitol (INS 421)
WHO — JECFA database: Mannitol (INS 421) evaluation summary and ADI
FAO/JECFA — Mannitol specification monograph (FAO JECFA Monographs)
FAO — JECFA additives details (INS 421: Mannitol) entry page
U.S. Code of Federal Regulations (as published via Cornell LII) — 21 CFR § 180.25 Mannitol
EUR-Lex — Regulation (EC) No 1333/2008 (consolidated): listing includes E 421 Mannitol
USP — Mannitol (excipient) harmonization posting (PDG)
International Trade Centre (ITC) — Trade Map tool overview (trade flow statistics platform)
Roquette — PEARLITOL® 200 GT (mannitol) product page (example of granular/direct compression grade marketing and physical form description)
ScienceDirect — Review: Mannitol in direct compression: production and functionality (International Journal of Pharmaceutics, 2025)

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