Development of South Korea's first pig that expresses gene scissors in its body
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Innovation & Technology
Published Nov 30, 2023
The Rural Development Administration in Korea has developed a pig that can edit genes within its own body using the Cas9 protein, also known as genetic scissors. This is the first time this has been achieved in Korea and it is the fourth country globally after China, Germany, and Denmark to develop such a pig. This development has advantages over previous methods as gene function can be confirmed more accurately and quickly in a living pig, and it has the potential to be used in various fields such as livestock improvement and medical research.
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The Rural Development Administration (Director Cho Jae-ho) announced that it has developed a pig that expresses the Cas9 (CRISPR associated protein 9) protein, widely known as genetic scissors, within its body. This is the first time that a pig that can edit genes in living pigs has been developed in Korea. Worldwide, it is fourth after China (2017, 2023), Germany (2021), and Denmark (2022). In order to overcome the disadvantages of using pigs to produce gene-edited animals for gene function research, the Rural Development Administration succeeded in producing pigs that express gene editing using somatic cell cloning methods. If Casnine gene scissors are in the body of a living pig, gene function can be immediately confirmed in the animal's body. This has the advantage of allowing the desired gene function to be confirmed more accurately and quickly than using cells cultured in the laboratory. Previously, gene editing in a living animal was possible only by inserting Casnine gene ...