Parent Product
Proteases
Sub Product
Cosmetic Grade Papain, Food Grade Papain, Industrial Grade Papain, Organic Papain, +1
HS Code
130219
Last Updated
2026-07-29
Key takeaways for search and sourcing teams
- Papain market coverage spans 131 countries.
- 150 exporter companies and 169 importer companies are indexed in the global supply chain intelligence network for this product.
- 149 supplier-linked transactions are summarized across the top 12 countries.
- 1 premium suppliers and 0 catalog items are currently listed.
- Wholesale sample entries: 0; farmgate sample entries: 0.
- Latest reference year in this page dataset is 2024.
- Page data last updated on 2026-07-29.
Global Supplier Transactions, Export Activity, and Price Benchmarks for Papain
Analyze 149 supplier-linked transactions across the top 12 countries, with monthly unit-price benchmarks to track export competitiveness and sourcing risk for Papain.
Papain Country YoY Change in Supplier Transactions and Export Momentum
Compare positive and negative YoY shifts in Papain to identify accelerating supplier markets and weakening export corridors.
Top YoY shifts for Papain: Indonesia (+317.8%), South Africa (+225.0%), Switzerland (+72.7%).
Papain Country-Level Supplier Transaction and Unit Price Summary
As of 2025-08, benchmark Papain country transaction counts with monthly unit price and volume to prioritize supplier and export markets.
In 2026-01, countries with visible Papain transaction unit prices: Belgium (59.56 USD / kg), China (29.00 USD / kg), India (9.70 USD / kg).
| Country | YoY Change | Transaction Count | 2025-08 | 2025-09 | 2025-10 | 2025-11 | 2025-12 | 2026-01 | 2026-02 | 2026-03 | 2026-04 | 2026-05 | 2026-06 | 2026-07 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| India | +20.3% | 56 | 11.94 USD / kg (4,827 kg) | 33.23 USD / kg (10,014.6 kg) | 8.58 USD / kg (276 kg) | 27.39 USD / kg (1,012.5 kg) | 8.61 USD / kg (100 kg) | 9.70 USD / kg (8,082 kg) | ||||||
| Uganda | +1.8% | 10 | 21.39 USD / kg (3,050 kg) | 18.41 USD / kg (10,100 kg) | - (-) | - (-) | - (-) | - (-) | ||||||
| Australia | +7.0% | 4 | 25.20 USD / kg (501 kg) | 25.20 USD / kg (801 kg) | - (-) | - (-) | - (-) | - (-) | ||||||
| South Africa | +225.0% | 3 | - (-) | - (-) | - (-) | - (-) | - (-) | - (-) | ||||||
| China | +40.2% | 34 | 29.29 USD / kg (2,401 kg) | 23.25 USD / kg (5,037 kg) | 21.01 USD / kg (700 kg) | 27.23 USD / kg (762 kg) | 31.85 USD / kg (55 kg) | 29.00 USD / kg (225 kg) | ||||||
| Belgium | -5.8% | 14 | 67.19 USD / kg (3,701.29 kg) | 59.66 USD / kg (570 kg) | - (-) | 63.93 USD / kg (500 kg) | 7.44 USD / kg (9,000 kg) | 59.56 USD / kg (1,140.23 kg) | ||||||
| Peru | - | 4 | - (-) | 9.92 USD / kg (90.72 kg) | - (-) | - (-) | 9.92 USD / kg (181.44 kg) | - (-) | ||||||
| Brazil | - | 3 | - (-) | 53.45 USD / kg (10 kg) | - (-) | - (-) | 15.83 USD / kg (1 kg) | - (-) | ||||||
| United States | +36.6% | 14 | 20.75 USD / kg (25 kg) | 25.76 USD / kg (43.79 kg) | 49.65 USD / kg (245.403 kg) | 25.34 USD / kg (8.97 kg) | - (-) | - (-) | ||||||
| Switzerland | +72.7% | 4 | - (-) | 185.34 USD / kg (0.88 kg) | - (-) | - (-) | - (-) | - (-) |
Papain Global Supply Chain Coverage
319 companies
150 exporters and 169 importers are mapped for Papain.
Exporters and importers can use Tridge Supply Chain Intelligence company profiles and analytics to identify counterparties for Papain, benchmark reach, and prioritize outreach by market.
Papain Export Supplier Intelligence, Trade Flows, and Price Signals
150 exporter companies are mapped in Tridge Supply Chain Intelligence for Papain. Exporters and importers can use company profiles and analytics to evaluate supplier coverage, trading activity, and route opportunities.
Papain Verified Export Suppliers and Premium Partners
1 premium Papain suppliers include country, industry, and contactability signals to prioritize credible export partners faster.
SM Empreendimentos Farmacêuticos Ltda.
Brazil
Others
Become a Premium Supplier to join the Tridge Supply Chain Network and advance your marketing and export channel strategy.
Papain Top Exporters and Supplier Profiles
Review leading exporter profiles while benchmarking against 150 total exporter companies in the Papain supply chain intelligence network. Exporters and importers can unlock company profiles and analytics to qualify partners faster.
(Taiwan)
Latest Export Transaction: 2026-06-29
Industries: Food Manufacturing
Value Chain Roles: Food Manufacturing
Exporting Countries: South Korea
Supplying Products: Enzymes, Proteases, Papain +2
(Democratic Republic of the Congo)
Latest Export Transaction: 2026-06-29
Industries: Food Manufacturing
Value Chain Roles: Farming / Production / Processing / PackingTrade
(China)
Latest Export Transaction: 2026-06-29
Employee Size: 51 - 100 Employees
Sales Revenue: USD 5M - 10M
Industries: Food ManufacturingOthers
Value Chain Roles: Food ManufacturingOthers
Exporting Countries: India, Pakistan, Vietnam, Mexico, Colombia
Supplying Products: Enzymes, Proteases, Papain +1
(Uganda)
Latest Export Transaction: 2025-09-30
Industries: Food WholesalersOthers
Value Chain Roles: Distribution / WholesaleTrade
Exporting Countries: India
Supplying Products: Enzymes, Proteases, Papain +1
(China)
Latest Export Transaction: 2026-06-29
Industries: Others
Value Chain Roles: Trade
Exporting Countries: Uzbekistan
Supplying Products: Enzymes, Proteases, Papain
(United Arab Emirates)
Latest Export Transaction: 2026-06-29
Sales Revenue: USD 10M - 50M
Industries: Food ManufacturingFood Services And Drinking PlacesOthers
Value Chain Roles: Distribution / WholesaleFood ManufacturingTrade
Papain Global Exporter Coverage
150 companies
Exporter company count is a key signal for Papain supply depth and sourcing optionality.
Use Supply Chain Intelligence analytics to narrow Papain opportunities by country, product, and value-chain role, then open company profiles to validate fit.
Top Exporting Countries for Papain (HS Code 130219) in 2024
For Papain in 2024, compare export volume and value across the top 10 supplier countries to map core supply structure.
| Rank | Country | Volume | Value |
|---|---|---|---|
| 1 | India | 18,857,269.283 kg | 539,817,304.363 USD |
| 2 | United States | 9,673,433 kg | 282,284,651 USD |
| 3 | Spain | 12,695,731.755 kg | 274,582,773.665 USD |
| 4 | Germany | 4,619,349.187 kg | 188,276,287.273 USD |
| 5 | Italy | 10,029,579 kg | 127,885,143.556 USD |
| 6 | Netherlands | 7,257,195.394 kg | 67,970,621.333 USD |
| 7 | Switzerland | 1,746,647.999 kg | 67,149,546.87 USD |
| 8 | South Korea | 2,213,473.122 kg | 61,603,865 USD |
| 9 | Mexico | 903,481.457 kg | 50,456,921 USD |
| 10 | Canada | 3,845,026.996 kg | 42,578,356.476 USD |
Papain Export Trade Flow and Partner Country Summary
Track Papain exporter-to-importer flows by value, volume, and share to uncover high-potential export routes.
Papain Import Buyer Intelligence, Demand Signals, and Price Benchmarks
169 importer companies are mapped for Papain demand intelligence. Use Supply Chain Intelligence company profiles and analytics to prioritize buyers, distributors, and downstream demand partners by market.
Papain Top Buyers, Importers, and Demand Partners
Review leading buyer profiles and compare them against 169 total importer companies tracked for Papain. Exporters and importers can use Supply Chain Intelligence company profiles and analytics to evaluate buyer quality and demand concentration.
(Jersey)
Latest Import Transaction: 2026-06-29
Industries: Brokers And Trade AgenciesFood WholesalersOthers
Value Chain Roles: -
(Uzbekistan)
Latest Import Transaction: 2026-06-29
Industries: Food WholesalersOthers
Value Chain Roles: -
(India)
Latest Import Transaction: 2026-06-17
Employee Size: 101 - 500 Employees
Sales Revenue: USD 10M - 50M
Industries: Animal ProductionBeverage ManufacturingFood Manufacturing
Value Chain Roles: Brazil, Kuwait, Ireland
(Jersey)
Latest Import Transaction: 2026-06-29
Industries: Brokers And Trade Agencies
Value Chain Roles: -
(Belgium)
Latest Import Transaction: 2026-06-29
Employee Size: 1 - 10 Employees
Sales Revenue: USD 10M - 50M
Industries: Food ManufacturingFood PackagingOthers
Value Chain Roles: -
(India)
Latest Import Transaction: 2026-06-29
Industries: Food Manufacturing
Value Chain Roles: -
Global Importer Coverage
169 companies
Importer company count highlights the current depth of demand-side visibility for Papain.
Use Supply Chain Intelligence analytics and company profiles to identify active Papain buyers, compare partner density by country, and refine GTM priorities.
Top Import Demand Countries for Papain (HS Code 130219) in 2024
For Papain in 2024, compare import volume and value across the top 10 demand countries to identify priority markets.
| Rank | Country | Volume | Value |
|---|---|---|---|
| 1 | United States | 45,602,650 kg | 1,144,058,187 USD |
| 2 | South Korea | 93,448,129.559 kg | 216,640,980 USD |
| 3 | Germany | 6,041,120.032 kg | 212,756,530.515 USD |
| 4 | Italy | 26,238,203.624 kg | 151,841,847.822 USD |
| 5 | Spain | 8,587,550.273 kg | 129,644,488.663 USD |
| 6 | Netherlands | 30,525,926.349 kg | 113,416,146.544 USD |
| 7 | Canada | 3,546,488.778 kg | 110,008,167.197 USD |
| 8 | Japan | 5,895,585.533 kg | 103,724,707.365 USD |
| 9 | Australia | 3,131,309.949 kg | 101,718,738.317 USD |
| 10 | Hong Kong | 654,760 kg | 68,560,205.131 USD |
Papain Import Trade Flow and Origin Country Summary
Analyze Papain origin-to-destination trade flows by value, volume, and share to monitor demand-side sourcing channels.
Classification
Product TypeIngredient
Product FormPowder
Industry PositionFood Processing Ingredient (Enzyme/Protease)
Market
Papain is a plant-derived proteolytic enzyme obtained from papaya (Carica papaya) latex and traded globally as a food-processing ingredient, including as a meat-tenderizing and protein-modifying enzyme. Supply availability is structurally linked to tropical papaya cultivation and to specialized collection/drying and standardization capacity that converts latex into stable powders for export. Demand is shaped by industrial protein processing needs (meat, hydrolysates, and certain beverage/processing applications) and by competition from substitute proteases (including microbial enzymes) that can offer more consistent performance or different regulatory positioning. International trade is typically organized through ingredient and enzyme distributors, with buyer emphasis on activity specification, microbiological limits, and compliance documentation in the destination market.
Market GrowthNot Mentioned
Major Producing Countries
- IndiaMajor papaya producer (papain source crop) according to FAOSTAT; papain supply is ultimately constrained by papaya production and latex collection economics.
- BrazilSignificant papaya producer (papain source crop) in FAOSTAT; relevant as a potential upstream base for papain extraction.
- MexicoSignificant papaya producer (papain source crop) in FAOSTAT; upstream relevance to papain availability.
- IndonesiaSignificant papaya producer (papain source crop) in FAOSTAT; upstream relevance to papain availability.
Specification
Physical Attributes
- Typically supplied as an off-white to light-colored powder or granulate that may be standardized with carriers to achieve target enzymatic activity.
- Hygroscopicity and dusting behavior can affect handling; moisture-barrier packaging is commonly used.
Compositional Metrics
- Proteolytic (enzymatic) activity is a primary commercial specification parameter; activity units and test method must be defined in the certificate of analysis.
- Moisture content and microbiological criteria are commonly specified for food-grade lots.
- Residue/contaminant specifications (e.g., heavy metals) may be included depending on buyer and destination-market requirements.
Grades
- Food grade (enzyme ingredient/processing aid)
- Compendial grade (where applicable, aligned to recognized compendia such as FCC/USP for identity and quality tests)
Packaging
- Moisture-barrier inner liners within fiber drums or multiwall bags for bulk shipments
- Smaller sealed pouches or HDPE containers for laboratory and specialty customers
ProcessingPerformance depends on process conditions (pH, temperature, and contact time); excessive heat can reduce activity.Compatibility with the food matrix and process aids (e.g., oxidizing agents) can affect enzyme effectiveness and stability.
Supply Chain
Value Chain
- Unripe papaya cultivation and fruit availability -> latex tapping/collection -> filtration/clarification -> drying -> milling and standardization to target activity -> quality testing and documentation -> packaging -> export via ingredient distributors
Demand Drivers
- Meat and poultry processing applications requiring proteolysis (e.g., tenderizing and texture modification)
- Protein hydrolysate production for flavors and functional ingredients
- Food processing applications where controlled protein breakdown supports process performance
Temperature
- Typically handled as a dry enzyme: keep cool and dry; minimize exposure to heat and humidity to protect activity.
- Avoid temperature abuse during storage and transport that can accelerate activity loss.
Risks
Crop Disease And Climate HighPapain supply is ultimately dependent on papaya cultivation and latex collection; major papaya diseases (including Papaya ringspot virus) and climate shocks in tropical production zones can reduce fruit availability and disrupt upstream latex supply, creating sudden tightness in papain availability and quality consistency.Maintain multi-origin sourcing strategies where feasible, qualify alternative proteases for critical applications (e.g., microbial proteases or bromelain), and use forward coverage/inventory buffers for high-dependency customers.
Regulatory Compliance MediumRegulatory treatment of enzymes can differ by jurisdiction (food additive vs. processing aid vs. enzyme preparation), affecting permitted uses, documentation, and labeling expectations for products made with papain.Confirm destination-market regulatory status and documentation needs (specifications, allergen statements, processing-aid declarations) with competent authorities and aligned buyer requirements before shipment.
Food Safety MediumAs a biologically derived ingredient, papain quality programs must manage microbiological criteria, foreign matter control, and batch-to-batch activity variability; inadequate controls can lead to non-conformance, recalls, or rejected shipments.Use supplier qualification with defined test methods for activity, microbiological limits, and contaminants; implement HACCP/ISO 22000-aligned controls and robust COA/traceability practices.
Market Substitution LowPapain competes with other proteases (including microbial enzymes) that may offer lower cost, more consistent activity profiles, or easier regulatory positioning for certain applications, pressuring demand in price-sensitive segments.Differentiate with application support, consistent activity standardization, and clear performance documentation tied to customer processes.
Sustainability
- Climate exposure in tropical production zones (extreme rainfall events, drought stress) affecting papaya yields and latex collection feasibility
- Agricultural input management (pesticide use and residue control) relevant to upstream papaya production and buyer assurance programs
- Processing waste and wastewater management in latex collection/drying operations where applicable
Labor & Social
- Worker safety in latex tapping and drying operations (chemical exposure risks and safe handling practices)
- Occupational sensitization risk from enzyme dust during handling, blending, and packaging of powdered enzymes; PPE and exposure controls are often required
FAQ
What is papain and what is it made from?Papain is a proteolytic (protein-breaking) enzyme obtained from papaya (Carica papaya), typically collected as latex from unripe fruit and then dried and standardized into a powder for industrial use.
What are common food-industry uses of papain in global trade?Papain is commonly used where controlled protein breakdown is needed, such as meat tenderizing/texture modification and certain protein-processing applications (including hydrolysates used in flavors and functional ingredients).
What are the most important buyer specifications for papain?Buyers typically focus on defined enzymatic activity (with a specified test method and units), moisture and microbiological criteria, and supporting compliance documentation for the destination market.
Sources
Papain Country Coverage for Suppliers, Export Flows, and Prices
Explore country-level Papain market pages for supplier coverage, trade flows, and price benchmarks.
All country market pages: United States, India, South Korea, China, Italy, Belgium, Brazil, Japan, Mexico, Guatemala, South Africa, Estonia, Malaysia, Egypt, Democratic Republic of the Congo, Peru, Denmark, Pakistan, Germany, France, Netherlands, Spain, Switzerland, Russia, Costa Rica, Finland, Canada, Ecuador, Lithuania, Philippines, Vietnam, Hong Kong, Singapore, United Kingdom, Poland, Australia, Ireland, Austria, Bangladesh, Bulgaria, United Arab Emirates, Turkiye, Uzbekistan, Chile, Thailand, Israel, Czechia, Slovenia, Argentina, Madagascar, Indonesia, Morocco, New Zealand, Sweden, Kenya, Romania, Hungary, Luxembourg, Saudi Arabia, Colombia, Dominican Republic, Portugal, Nepal, Andorra, Albania, Armenia, Azerbaijan, Bosnia and Herzegovina, Burkina Faso, Bahrain, Burundi, Benin, Bermuda, Bolivia, Bahamas, Botswana, Belize, Ivory Coast, Cuba, Cyprus, Ethiopia, Fiji, Greece, Honduras, Croatia, Iran, Iceland, Jamaica, Jordan, Kyrgyzstan, Cambodia, Kuwait, Kazakhstan, Laos, Sri Lanka, Liberia, Lesotho, Latvia, Moldova, Montenegro, Macedonia, Myanmar [Burma], Mongolia, Macao, Malta, Mauritius, Maldives, Malawi, Mozambique, Namibia, Niger, Nigeria, Nicaragua, Norway, Oman, Panama, Paraguay, Qatar, Serbia, Slovakia, Senegal, El Salvador, Swaziland, Togo, Tunisia, Tanzania, Ukraine, Uganda, Uruguay, Zambia, Zimbabwe
Related Papain Product Categories
Browse parent, sub, derived, and raw-material product market pages related to Papain.
Parent product: Proteases
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