PRRS virus is becoming increasingly aggressive in pigs in Europe

Published 2024년 9월 18일

Tridge summary

At the Hipra seminar in Valburg, Gelderland, Hipra's Nauwynck discussed the strategies used by the PRRS virus to evade the pig's immune system, focusing on its ability to enter white blood cells and avoid detection. The virus's proteins and sugars enable attachment to white blood cells, and its RNA can be deciphered using whole genome sequencing. The virus's genetic variability was highlighted, with some proteins showing consistent codes while others do not, and not all mutations lead to increased virus aggressiveness. The event also covered the transportation of piglets and fattening pigs as a significant risk factor for virus spread, emphasizing the importance of biosecurity and compliance with regulations to prevent PRRS virus introduction and spread on farms.
Disclaimer:The above summary was generated by Tridge's proprietary AI model for informational purposes.

Original content

During the seminar 'Thinking differently is doing differently' organised by Hipra last week in Valburg, Gelderland, Nauwynck spoke about various mechanisms that the PRRS virus uses to infect a pig and bypass the immune system. The aim of the PRRS virus is to enter a white blood cell. To this end, the virus has various proteins and sugars on the outside. This allows it to attach itself to white blood cells. The proteins and sugars also ensure that the virus eventually ends up in the white blood cell. Defence mechanism does not work The clever thing about the PRRS virus is that the white blood cell eventually dies and that newly formed virus can be absorbed by new cells via cell vesicles without being recognised by the pig's defence mechanism and immunity. The genetic code for those proteins with which the PRRS virus can enter the white blood cell and multiply can be recorded using the technique of 'whole genome sequencing', in which the entire genetic information is deciphered. ...
Source: Nieuwe Oogst

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