The article expresses concerns regarding the potential negative impacts of globalization and Brexit on agriculture in Central Northern and Southern Italy. It highlights the threat to 'Made in Italy' products from the economic globalization desired by the European Union and the potential negative effects on farmers in Southern Italy and Sicily from CETA and North African products. The article also discusses the negative effects on durum wheat producers and olive oil producers in Southern Italy from foreign wheat and olive oil. Additionally, it touches on the competition from Romanian sheep's milk and the impact of CETA on southern Italian agriculture. The potential implications of Brexit for agriculture in Central and Northern Italy are also discussed.