The European Food Safety Authority (EFSA) has outlined detailed surveillance and risk reduction strategies for avian influenza, emphasizing the importance of both emergency and preventive vaccination. The guidance includes specific recommendations on the types of poultry to be targeted, the number of animals to be tested, diagnostic methods, and the timing of sampling. For emergency vaccination against highly pathogenic avian influenza (HPAI), the focus is on early detection, considering poultry type and flock size, whereas preventive vaccination involves monthly virological testing of dead birds. EFSA highlights the necessity of passive surveillance for all flocks, vaccinated or not, and stresses the importance of vaccination within an integrated disease control strategy, alongside strategic surveillance and high biosecurity levels.