Nissan Chemical's New Herbicide Iptriazopyrid: First HPPD Inhibitor for Foliar Application in Rice, to Be Launched in 2027

Published 2025년 6월 17일

Tridge summary

Core Tip: According to the World Agricultural Chemical Network's Chinese website, recently, Nissan Chemical Corporation and the National Institute of Advanced Industrial Science and Technology jointly released an important research achievement, successfully elucidating the mechanism of action for the new rice herbicide iptriazopyrid. Nissan Chemical stated that the company will continue to promote the global development of iptriazopyrid, with the goal of achieving product commercialization and market launch by 2027. Additionally, the Indian government has recently approved the molecule under the 1968 Pesticide Act, marking the gradual entry of iptriazopyrid into the Indian market.

Original content

It is reported that the mechanism of action of iptriazopyrid is to inhibit the key enzyme of carotenoid synthesis—4-hydroxyphenylpyruvate dioxygenase (HPPD). The research team confirmed through crystal structure analysis technology that the compound can specifically bind to the HPPD enzyme, thereby exerting herbicidal effects. HPPD inhibitors are classified as Group 27 in the Global Herbicide Resistance Action Committee (HRAC). Iptriazopyrid is expected to become the first foliar-applied herbicide in rice fields classified as Group 27, a characteristic that gives it significant importance in resistant weed management. Research shows that iptriazopyrid has excellent selective action characteristics. The compound demonstrates strong herbicidal activity against major rice field weeds such as barnyard grass, and is not metabolized by weed plants; conversely, rice plants can rapidly metabolize the compound, ensuring high crop safety. This selective metabolic characteristic is of ...

Source: Foodmate