The U.S. officially approves the registration of the active ingredient trifluridin from Xianzhengda.

Published 2025년 11월 13일

Tridge summary

According to the EPA's risk assessment, when used as directed on the label, cyclobutrifluram poses no risk to human health. Furthermore, the EPA has implemented a series of mitigation measures to ensure that the use of this pesticide does not adversely affect endangered species and their habitats.

The introduction of cyclobutrifluram will provide a strong supplement to integrated pest management (IPM) plans. This ingredient can be rotated with other nematicides to effectively reduce the risk of pests developing resistance in crops and lawns. To ensure the safety of cyclobutrifluram for non-target species, the product label explicitly requires: using a coarse droplet spray for lawns and limiting the spraying range to avoid harming flowering plants; additionally, measures should be taken during use to cover or collect spilled seeds to reduce potential risks.

Cyclobutrifluram (cyclobutrifluram, trade name Tymirium®, CAS number 1460292-16-3) is a new generation SDHI class fungicide/nematicide discovered by Syngenta in 2013, another technological breakthrough following Bayer's fluopyram. This product demonstrates excellent broad-spectrum efficacy in its control spectrum, effectively preventing and controlling diseases such as wheat crown rot caused by Fusarium graminearum, rice bakanae disease caused by Fusarium fujikuroi, and tomato gray mold caused by Botrytis cinerea, and it also performs excellently in the field of nematicides, capable of preventing and controlling pine wood nematode disease, sweet potato stem nematode disease, and other stubborn nematode diseases. Currently, cyclobutrifluram has completed registration in Australia, Argentina, and Brazil, and is in the process of registration in Canada.

Original content

According to the EPA's risk assessment, when used as directed on the label, cyclobutrifluram poses no risk to human health. Furthermore, the EPA has implemented a series of mitigation measures to ensure that the use of this pesticide does not adversely affect endangered species and their habitats. The introduction of cyclobutrifluram will provide a strong supplement to integrated pest management (IPM) plans. This ingredient can be rotated with other nematicides to effectively reduce the risk of pests developing resistance in crops and lawns. To ensure the safety of cyclobutrifluram for non-target species, the product label explicitly requires: using a coarse droplet spray for lawns and limiting the spraying area to avoid harming flowering plants; additionally, measures should be taken during use to cover or collect any spilled seeds to reduce potential risks. Cyclobutrifluram (Tymirium®, CAS number 1460292-16-3) is a new generation SDHI fungicide/nematicide discovered by Syngenta ...
Source: Foodmate

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