A team of researchers from Hunan Agricultural University and the Oil Crop Research Institute of the Chinese Academy of Agricultural Sciences have unraveled the long-standing mysteries surrounding the origin and domestication of mustard. Publishing their findings in the prestigious journal 'Nature-Genetics', they used whole-genome sequencing and a unique local cultivar, 'Sichuan Yellow Seed', to reconstruct the mustard genome. The team's comprehensive analysis, which included research on 38 global regions and 480 mustard germplasms, revealed that mustard originated in the Middle East around 8000-14000 years ago and diversified into six distinct groups. This breakthrough not only provides crucial insights into mustard's evolution but also offers a solid foundation for utilizing mustard germplasm resources and accelerating genome selection breeding, with potential implications for enhancing mustard breeding efficiency.