The article reports a severe alarm raised due to the detection of African swine fever (ASF) in the Dominican Republic, as confirmed by the USDA. This development has prompted Panama and Mexico to take stringent measures to prevent the spread of the disease. In Panama, a shipment of 80 pounds of pork from the Dominican Republic was intercepted, leading to a zoosanitary alert. Meanwhile, Mexico has initiated a comprehensive plan, involving over a thousand technicians and 112 canine pairs, to safeguard its pig population. The countries are leveraging their efforts to maintain their pig production without experiencing disruptions due to ASF, in the midst of the COVID-19 pandemic.