The 2023 Aquaculture Ghana Conference highlighted the challenges facing the domestic aquaculture industry, with a particular focus on the significant cost of feed and disease prevalence. The rising cost of feed, driven by increasing prices of essential ingredients like maize and soya beans, has led to a surge in imported feed, increasing the nation's import bills and straining the local currency. These challenges are threatening the sustainability of the industry and have been emphasized by the Chairman of the Fisheries Commission Board, Professor Francis Nunoo, and the Chief Executive of the Association of Ghana Industries, Seth Akwaboah. In response, efforts are being made to build local capacity in fish disease management and to invest in technology to explore shrimp mariculture, reflecting the industry's efforts to adapt and grow amidst these challenges.