Germany has reported its first outbreak of foot-and-mouth disease in nearly 40 years, with three buffaloes dying from the disease in Hönow, Brandenburg. The disease, which affects cattle, pigs, sheep, and goats, causes fever and blisters in the mouth. Authorities have implemented containment measures, including the slaughter of affected animals, and have established exclusion and monitoring zones. The source of the infection is under investigation by the German Ministry of Agriculture. The last cases of foot-and-mouth disease in Germany were recorded in 1988. The disease is prevalent in the Middle East, Africa, Asia, and parts of South America, and there are concerns it may be spread to Europe through illegally imported animal products.