The articles highlights the economic challenges faced by the Peruvian regions of Puno and Tumbes due to land border closures, either due to the pandemic or illegal trade activities. The closure has significantly impacted the tourism sector, leading to the focus on sustainable economies, particularly in livestock and agriculture. Puno has seen a slight growth in livestock and agricultural production, while Tumbes, with its international bridge closed for 18 months, has experienced a decrease in income from internal taxes. The region is seeking to accelerate vaccine doses arrival to reopen the border and control illegal access bridges to prevent further infections and economic activities reactivation.