The Culiacan Valley is conducting trials to develop safflower varieties with increased productivity and disease resistance, focusing on those that produce monounsaturated and oleic acids. The Mexican Safflower Genetic Improvement Program is aiming to adapt genotypes to different production areas and is evaluating 15 safflower genotypes for productivity. In the experimental field, the genotypes C45-2-MOC, C63-0Y, and Ciano OL showed the highest yields in the 2023-2024 evaluation cycle. No cases of ramularia blotch were reported in both evaluation cycles.