A study by Prof. Song Xianjun's group at the Institute of Botany of the Chinese Academy of Sciences has identified a gene network regulating seed size in rice. The research reveals a crucial pathway involving the OsTIR1–OsIAA10–OsARF4 cascade and the phosphorylation of the Thousand-grain weight on chromosome 3 (TGW3) protein on OsIAA10. This finding is crucial as grain size is a key factor in rice yield and quality. The discovery of this phosphorylation-driven auxin signaling pathway could be used to enhance the agronomic trait in crops.