Parent Product
Mannitol
Last Updated
2026-05-14
Key takeaways for search and sourcing teams
- Pharmaceutical Grade Mannitol market coverage spans 2 countries.
- 4 exporter companies and 1 importer companies are indexed in the global supply chain intelligence network for this product.
- 1 supplier-linked transactions are summarized across the top 1 countries.
- 0 premium suppliers and 0 catalog items are currently listed.
- Wholesale sample entries: 0; farmgate sample entries: 0.
- Page data last updated on 2026-05-14.
Global Supplier Transactions, Export Activity, and Price Benchmarks for Pharmaceutical Grade Mannitol
Analyze 1 supplier-linked transactions across the top 1 countries, with monthly unit-price benchmarks to track export competitiveness and sourcing risk for Pharmaceutical Grade Mannitol.
Pharmaceutical Grade Mannitol Country YoY Change in Supplier Transactions and Export Momentum
Compare positive and negative YoY shifts in Pharmaceutical Grade Mannitol to identify accelerating supplier markets and weakening export corridors.
Pharmaceutical Grade Mannitol Country-Level Supplier Transaction and Unit Price Summary
As of 2025-06, benchmark Pharmaceutical Grade Mannitol country transaction counts with monthly unit price and volume to prioritize supplier and export markets.
In 2025-11, countries with visible Pharmaceutical Grade Mannitol transaction unit prices: India (20.77 USD / kg).
| Country | YoY Change | Transaction Count | 2025-06 | 2025-07 | 2025-08 | 2025-09 | 2025-10 | 2025-11 | 2025-12 | 2026-01 | 2026-02 | 2026-03 | 2026-04 | 2026-05 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| India | - | 1 | - (-) | - (-) | - (-) | - (-) | - (-) | 20.77 USD / kg (50 kg) |
Pharmaceutical Grade Mannitol Global Supply Chain Coverage
5 companies
4 exporters and 1 importers are mapped for Pharmaceutical Grade Mannitol.
Exporters and importers can use Tridge Supply Chain Intelligence company profiles and analytics to identify counterparties for Pharmaceutical Grade Mannitol, benchmark reach, and prioritize outreach by market.
Pharmaceutical Grade Mannitol Export Supplier Intelligence, Trade Flows, and Price Signals
4 exporter companies are mapped in Tridge Supply Chain Intelligence for Pharmaceutical Grade Mannitol. Exporters and importers can use company profiles and analytics to evaluate supplier coverage, trading activity, and route opportunities.
Pharmaceutical Grade Mannitol Top Exporters and Supplier Profiles
Review leading exporter profiles while benchmarking against 4 total exporter companies in the Pharmaceutical Grade Mannitol supply chain intelligence network. Exporters and importers can unlock company profiles and analytics to qualify partners faster.
(Singapore)
Latest Export Transaction: 2025-07-28
Industries: Others
Value Chain Roles: TradeDistribution / Wholesale
Exporting Countries: United States
Supplying Products: Mannitol, Pharmaceutical Grade Mannitol
(China)
Latest Export Transaction: 2026-04-12
Employee Size: Over 1000 Employees
Sales Revenue: USD Over 1B
Industries: Food Manufacturing
Value Chain Roles: Farming / Production / Processing / PackingFood ManufacturingTrade
Exporting Countries: Pakistan, Indonesia, United States, Bangladesh
Supplying Products: Mannitol, Alginate, Pharmaceutical Grade Mannitol
(Egypt)
Latest Export Transaction: 2026-04-12
Employee Size: 101 - 500 Employees
Industries: Food WholesalersCrop Production
Value Chain Roles: Distribution / WholesaleFarming / Production / Processing / Packing
Exporting Countries: Russia
Supplying Products: Fresh Cherry, Frozen Potato, Fresh Apple +2
(India)
Latest Export Transaction: 2025-11-18
Employee Size: 101 - 500 Employees
Sales Revenue: USD 10M - 50M
Industries: Food Manufacturing
Value Chain Roles: TradeFood Manufacturing
Exporting Countries: United States, Nepal, Pakistan, Indonesia, Mexico, Vietnam, Sri Lanka, Taiwan, Algeria, Netherlands
Supplying Products: Garcinia Extract, Vitamin D, Vitamin B12 +5
Pharmaceutical Grade Mannitol Global Exporter Coverage
4 companies
Exporter company count is a key signal for Pharmaceutical Grade Mannitol supply depth and sourcing optionality.
Use Supply Chain Intelligence analytics to narrow Pharmaceutical Grade Mannitol opportunities by country, product, and value-chain role, then open company profiles to validate fit.
Pharmaceutical Grade Mannitol Import Buyer Intelligence, Demand Signals, and Price Benchmarks
1 importer companies are mapped for Pharmaceutical Grade Mannitol demand intelligence. Use Supply Chain Intelligence company profiles and analytics to prioritize buyers, distributors, and downstream demand partners by market.
Pharmaceutical Grade Mannitol Top Buyers, Importers, and Demand Partners
Review leading buyer profiles and compare them against 1 total importer companies tracked for Pharmaceutical Grade Mannitol. Exporters and importers can use Supply Chain Intelligence company profiles and analytics to evaluate buyer quality and demand concentration.
(India)
Latest Import Transaction: 2026-04-12
Employee Size: 11 - 50 Employees
Sales Revenue: USD 10M - 50M
Industries: Others
Value Chain Roles: -
Global Importer Coverage
1 companies
Importer company count highlights the current depth of demand-side visibility for Pharmaceutical Grade Mannitol.
Use Supply Chain Intelligence analytics and company profiles to identify active Pharmaceutical Grade Mannitol buyers, compare partner density by country, and refine GTM priorities.
Classification
Product TypeIngredient
Product FormCrystalline powder (pharmaceutical grade)
Industry PositionFood Additive and Pharmaceutical Excipient
Market
Pharmaceutical-grade mannitol (INS 421) is a globally traded polyol used as both a food additive (e.g., sweetener/bulking/humectant functions) and a pharmaceutical excipient for solid oral and other formulations. International trade is commonly tracked under HS 290543, with 2024 UN Comtrade-derived data indicating major export nodes in France, China, the United States, Italy, and the Netherlands. Key import demand centers in 2024 include India, the United States, Japan, Germany, and the Netherlands, reflecting both pharmaceutical manufacturing and broader ingredient demand. Market dynamics are strongly shaped by compendial compliance expectations (e.g., pharmacopoeial monographs) and supplier qualification/quality assurance requirements for regulated pharmaceutical supply chains.
Major Producing Countries
- FranceLeading exporter by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS), indicating significant production capacity.
- ChinaTop-tier exporter in 2024 for HS 290543 (UN Comtrade via World Bank WITS), indicating significant production capacity.
- United StatesMajor exporter in 2024 for HS 290543 (UN Comtrade via World Bank WITS); also a large regulated end-use market.
- ItalyMajor exporter in 2024 for HS 290543 (UN Comtrade via World Bank WITS).
- NetherlandsMajor exporter in 2024 for HS 290543 (UN Comtrade via World Bank WITS); also a major import market and EU distribution hub.
Major Exporting Countries
- FranceTop exporter by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$161.4M).
- ChinaTop exporter by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$79.1M).
- United StatesTop exporter by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$34.1M).
- ItalyTop exporter by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$22.6M).
- NetherlandsTop exporter by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$17.5M).
Major Importing Countries
- IndiaTop importer by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$49.8M).
- United StatesTop importer by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$47.8M).
- JapanTop importer by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$28.9M).
- GermanyTop importer by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$20.1M).
- NetherlandsTop importer by value in 2024 for HS 290543 (UN Comtrade via World Bank WITS: ~US$19.3M).
Specification
Physical Attributes
- Odorless white crystalline powder or free-flowing granules with a sweet taste (PubChem).
- Low hygroscopicity is emphasized for pharmaceutical excipient grades used in solid dosage forms (Roquette; Merck).
Compositional Metrics
- Pharmacopeial/compendial testing is a core commercial expectation for pharmaceutical-grade material (e.g., USP PDG harmonized Mannitol monograph).
- For excipient grades intended for parenteral manufacturing, endotoxin-related testing/labeling considerations may apply per pharmacopeial requirements (USP PDG harmonized Mannitol monograph; supplier low-endotoxin grades exist commercially).
Grades
- Food additive grade: INS 421 (Codex GSFA / GSFA Online).
- Pharmaceutical excipient grade: sold as multi-compendial material (e.g., labeled as meeting EP/USP-NF/JP on commercial product documentation).
Packaging
- Common pharma supply formats include multi-kilogram packs (e.g., 2.5 kg and 25 kg packs are listed for directly compressible mannitol excipient products).
ProcessingCommercially available forms include crystalline and spray-dried/directly compressible grades; polymorph/solid-state control can be relevant to compaction behavior (industry technical literature).
Supply Chain
Value Chain
- Sugar/starch-derived feedstock (e.g., glucose/invert sugar) -> reduction/hydrogenation to mannitol -> purification -> crystallization -> drying/milling or spray-drying (for directly compressible grades) -> compendial QC testing -> packaging -> distribution to pharmaceutical and food manufacturers.
Demand Drivers
- Pharmaceutical solid oral dose manufacturing demand for directly compressible excipients (e.g., direct compression, wet granulation, roller compaction applications are promoted for mannitol excipient grades).
- Biopharmaceutical formulation use cases where low-endotoxin, high-purity grades are specified for downstream/protein stabilization applications (supplier documentation).
- Food additive demand for INS 421 functional roles (sweetener, bulking agent, humectant, stabilizer, thickener, carrier, anticaking agent) under Codex GSFA provisions.
Temperature
- Generally shipped/stored as a dry, stable powder under ambient conditions; moisture protection remains important even for low-hygroscopicity grades used in pharmaceutical manufacturing.
Risks
Quality And Regulatory Compliance HighThe most disruptive global risk is a quality or compliance failure in pharmaceutical-grade mannitol supply (e.g., out-of-spec impurities/microbial/endotoxin controls for intended use), because regulated customers may be unable to switch suppliers quickly without requalification and, in some cases, regulatory change control. Pharmacopeial monographs for Mannitol include expanded testing expectations and explicitly address endotoxin-related considerations when the excipient is intended for parenteral dosage-form manufacture.Pre-qualify at least two suppliers, align to pharmacopeial requirements for intended use, and use risk-based supplier auditing/third-party excipient GMP/GDP certification where appropriate (e.g., EXCiPACT) with robust incoming QC.
Supply Concentration MediumTrade data indicate a limited set of exporting countries account for a large share of reported global exports under HS 290543 (notably France and China among the largest exporters by value in 2024). Disruptions at major plants or logistics corridors can tighten availability, especially for multi-compendial or special-quality grades.Diversify sourcing across multiple exporting regions and maintain safety stock for critical grades (e.g., low-endotoxin or directly compressible specifications).
Food Additive Regulatory Compliance MediumAs INS 421, mannitol’s permitted uses and maximum levels vary by food category under Codex GSFA; downstream food manufacturers must ensure formulation and labeling compliance with applicable national implementations of additive standards.Validate intended-use categories against Codex GSFA (and relevant national regulations) and ensure correct additive labeling and specifications documentation.
Trade Policy And Tariffs LowMannitol is a distinct HS subheading (HS 290543) used for customs and trade statistics; changes in tariffs, trade remedies, or documentation requirements can affect landed cost and sourcing decisions across import markets.Maintain HS classification discipline and monitor tariff updates in destination markets for HS 290543, especially when re-routing supply across intermediating hubs.
Sustainability
- Energy and carbon exposure from industrial reduction/hydrogenation and drying operations used in commercial manufacture of mannitol.
- Agricultural feedstock linkage (sugars/starch hydrolysates) can transmit upstream crop and energy-price volatility into polyol cost structures.
Labor & Social
- Pharmaceutical excipient supply-chain integrity and supplier qualification expectations (GMP/GDP) place emphasis on traceability, auditability, and change control across manufacturers and distributors.
FAQ
What trade code is commonly used to track mannitol in global customs statistics?Mannitol is commonly tracked under HS code 290543 in the Harmonized System for trade statistics and customs classification.
Which countries are leading exporters and importers of mannitol in recent UN Comtrade-derived data?In 2024 UN Comtrade-derived data (via World Bank WITS) shows France, China, the United States, Italy, and the Netherlands among the top exporters by value, while India, the United States, Japan, Germany, and the Netherlands are among the top importers by value.
What is mannitol’s role as a food additive under Codex?Codex GSFA lists mannitol as INS 421 and identifies functional classes including sweetener, bulking agent, humectant, stabilizer, thickener, carrier, anticaking agent, with permitted uses and limits varying by food category.
Why does pharmaceutical-grade mannitol often require tighter quality controls than commodity sweeteners?Pharmaceutical-grade mannitol is used as an excipient in regulated medicines, so it is typically supplied to meet pharmacopeial standards and excipient GMP expectations; pharmacopeial guidance for Mannitol also highlights endotoxin-related testing/labeling considerations when intended for parenteral dosage-form manufacture.
Sources
Pharmaceutical Grade Mannitol Country Coverage for Suppliers, Export Flows, and Prices
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Related Pharmaceutical Grade Mannitol Product Categories
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Parent product: Mannitol
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