US researchers develop vaccines for Clostridial dermatitis in turkeys

Published 2024년 12월 11일

Tridge summary

The USPOULTRY Foundation and North Carolina State University have completed a study funded by Prestage Farms on using nontoxic segments of C. septicum alpha toxin as a vaccine against Clostridial dermatitis in turkeys. The research identified two probiotic Lactococcus lactis-based vaccines expressing ntATX antigens, which protected turkeys against the disease when administered via parenteral and oral routes. Clostridial dermatitis, caused by Clostridium septicum, is a significant economic problem for the poultry industry.
Disclaimer:The above summary was generated by Tridge's proprietary AI model for informational purposes.

Original content

USPOULTRY and the USPOULTRY Foundation are announcing the completion of a funded research project by researchers at North Carolina State University, which not only showed that nontoxic segments of C. septicum alpha toxin possess a protective ability against experimental Clostridial dermatitis infection of turkeys and can be suitable vaccine candidates, but also both parenteral and oral routes of vaccination can protect turkeys against Clostridial dermatitis. The research was made possible in part by an endowing USPOULTRY Foundation gift from Prestage Farms. The research is part of USPOULTRY's comprehensive research program encompassing all phases of poultry and egg production and processing. A summary of the completed project: Project #BRF-014, Development of a Probiotic-Based Recombinant Oral Vectored-Vaccine Against Clostridial Dermatitis in Turkeys - Dr. Ravi Kulkarni, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State ...
Source: Provisioner

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