The INTA made a strategic leap in the genetic improvement of rice by achieving the in vitro regeneration of plants of the Gurí INTA CL variety, one of the most widely used in national and international production systems. The advance, led by the Ewald A. Favret Institute of Genetics (IGEAF) of INTA, opens the door to the design of gene editing protocols applied directly on elite cultivars, with potential impact on productivity, health, and quality of the grain. In this framework, researchers from the Biotechnological Improvement of Cereals group of the INTA's Institute of Genetics took the first steps towards the development of gene editing protocols in rice cultivars (Oryza sativa L) from the Institution's breeding program. As part of this advance, they managed to regenerate in vitro and make stable modifications in the genome of a set of local commercial rice varieties of productive interest, developed by the Rice Genetic Improvement Program of the INTA's Agricultural Experiment ...