The National Biosafety Authority of Ghana has approved a genetically modified (GM) cowpea, marking a significant milestone as the country's first GM crop for commercialization. This event marks Ghana's entry into the ranks of countries like Nigeria and potentially Burkina Faso, where GM cowpea is set to be cultivated for its pest resistance, aiming to enhance food security and reduce the use of harmful insecticides. However, its adoption faces challenges, including concerns from civil society groups, the need for additional regulatory approvals, and issues such as pest resistance and cost. The outcome hinges on factors like agricultural performance, environmental impacts, and stakeholder perceptions, with ongoing debates highlighting the complex interplay of science, agriculture, and society in shaping food systems.