Potatoes are experiencing a surge in demand in eastern Africa, unfortunately, production levels have dropped due to pests, disease, and poor seed quality. The introduction of potato cyst nematodes, specifically Globodera rostochiensis and Globodera pallida, has caused significant yield losses. Research is underway to identify chemicals that could stimulate the nematodes to hatch, potentially leading to their demise. Other control measures include crop rotation, using disease-free seed, and exploring resistant potato varieties. A collaborative effort is being made to assess the effectiveness of these strategies.