Researchers at The Roslin Institute, University of Edinburgh, have identified several areas of chickens' DNA that may play a role in their natural resistance to bird flu. The study, which analyzed the DNA of chickens that survived a highly infectious avian influenza outbreak in 2015, found specific regions across 9 different areas of the chicken genome where genetic variations could be linked to resistance. The research has identified several genes associated with the immune system and the birds' response to the virus, including the gene ANP 32A, which is already known to play a role in how animals respond to bird flu. This finding could help develop strategies to protect poultry and inform public health as highly pathogenic avian influenza outbreaks become more common and infect a wider host-range.