Genetic clues could help breed chickens resilient to bird flu in the UK

Published Nov 22, 2024

Tridge summary

Researchers at The Roslin Institute, University of Edinburgh, have identified several areas of chickens' DNA that may play a role in their natural resistance to bird flu. The study, which analyzed the DNA of chickens that survived a highly infectious avian influenza outbreak in 2015, found specific regions across 9 different areas of the chicken genome where genetic variations could be linked to resistance. The research has identified several genes associated with the immune system and the birds' response to the virus, including the gene ANP 32A, which is already known to play a role in how animals respond to bird flu. This finding could help develop strategies to protect poultry and inform public health as highly pathogenic avian influenza outbreaks become more common and infect a wider host-range.
Disclaimer:The above summary was generated by Tridge's proprietary AI model for informational purposes.

Original content

Several areas of chickens’ DNA may influence natural resistance against bird flu, according to research. The study, which was carried out by The Roslin Institute, University of Edinburgh, looked at chickens that survived a major outbreak of highly infectious avian influenza in 2015 and found genetic clues that could help protect chickens from deadly bird flu outbreaks. Using blood samples, the team analysed the DNA from chickens that survived the viral outbreak and compared them with that of uninfected, presumed susceptible birds, seeking differences that could reveal genes linked to resistance. The birds studied survived a particularly lethal avian influenza outbreak, which saw a mortality rate of over 99%. Genes and the immune system The study showed uncovered specific regions across 9 different areas of the chicken genome where genetic variations appeared to play a role. Although no single gene fully explained why some chickens survived, the study pinpointed several genes ...
Source: Poultryworld

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