A new vaccination campaign against Brucellosis for cattle and buffaloes in São Paulo, Brazil, will be conducted throughout the year. The vaccine, which must be administered by registered veterinarians, replaces the owner's declaration of vaccination with a system where the veterinarian registers the certificate in the GEDAVE system. The campaign also introduces a new identification system using buttons for animals that have been vaccinated with B19 or RB 51 vaccines, and requires producers to regularize any discrepancies between the number of vaccinated animals and declared herd. The use of the button is currently limited to São Paulo.