The Ministry of Agriculture in Spain is working to amend Royal Decree 53/2013 to fulfill the requirements of the EU 2024/1262 Delegated Directive, which aims to enhance the care and protection of animals used in scientific research and education. The directive, which must be implemented by December 2025, focuses on species like cephalopods, zebrafish, and passerine birds, addressing recent scientific and ethical advancements. The modifications include upgraded housing conditions, less painful slaughter methods, and administrative changes to clarify the operation of evaluation and supervision bodies. The scientific community is encouraged to participate in a public consultation to identify potential challenges and to ensure compliance with the new regulations, which could include increased inspections and potential legal actions for non-compliance. The changes are seen as a necessary step towards a more ethical approach in Spain's animal research and production sectors.