Brazil: Study of several species helps to understand avian flu

Published Mar 27, 2023

Tridge summary

A study by Roslin scientists has discovered that biological factors play a role in how different bird species respond to avian flu. The research, which compared six poultry species with varying levels of resistance to the disease, found that pigeons, known for their resistance, have high levels of genes involved in the immune response to infection. Other genes, especially those linked to the nervous system, were also identified as potentially contributing to resistance. The rapid innate immune response to infection was found to be crucial, with delayed reactions leading to worse outcomes. The study, published in Frontiers in Cellular and Infection Microbiology, could help develop commercial birds resistant to avian flu.

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Original content

The response to infection in birds – from chickens to crows – points to biological factors linked to disease resistance. Investigations of how various bird species respond to avian flu have provided insights into the disease. The findings, from a study by Roslin scientists, point to key immune processes and genes that may play a role in how different species respond to infection. The results of the study may help in the development of commercial birds resistant to the disease. Varied reactions The researchers examined the response to mild and severe flu strains in six poultry species, chicken and turkey, which are known to be susceptible to the disease; duck and crow, which tolerate and spread disease; and goose and pigeon, recognized as highly resistant. The team sought to identify biological differences that affect the effects of infection. In chickens and turkeys, exposure has been found to lead to the accumulation of very high amounts of virus in various organs, including the ...

Source: Avistie